Discovering Organoids

Thymistem supports Marta Mosquera further her scientific skills of developing lab based organoids at The University of Cambridge

Last August I had the great opportunity to attend the workshop "Discovering Organoids: Establishment, Culture and Manipulation" organised by CamBioscience (part of Plurimes) in Homerton College, Cambridge UK. The excellent location of the course provided a great environment for scientific interaction and learning, as well as for enjoying history while walking through the ancient streets of the city. The programme consisted in a series of lectures taught by world's leading experts in the field of organoids combined with practical training sessions. During the lectures, we were lucky enough to listen firsthand to the researchers that have first established stomach, pancreas and liver organoids, and to learn the basic concepts regarding organoids and possible applications of this novel culture technology. But more importantly, we learnt about the challenges these researchers faced during the process of development of an organoid from a new organ, and the steps they followed to overcome the difficulties which eventually led them to a successful result. During the practical sessions, small groups were formed and we were trained to successfully establish, maintain and manipulate liver intestinal organoid cultures from primary mouse liver samples. Having the chance to put into practice the concepts that we were previously taught was indeed priceless. This course has provided us with new tools to culture and characterize thymic epithelial stem cells, which will definitely help us to accomplish our main goal in Thymistem: thymic regeneration. Personally, it has been a highly inspiring and motivating experience that has certainly influenced the way I face new scientific projects and challenges.

By Marta Mosquera, Universidad Autónoma de Madrid