The Thymistem project has now ended, running for four years from 1/12/2013-31/9/2017
Our nine research teams are collaborating to advance understanding of the cells within the thymus, one of the central organs in the immune system. Our goal is to develop and test novel approaches for thymus replacement or regeneration, in order to pave the way for new stem cell based therapies to repair the thymus.
Previous clinical research has shown that transplanting a thymus into patients can be an effective way to repair and restore the immune system. The thymus tissue used for these transplants came from patients undergoing heart surgery and would normally have been discarded, since the thymus is removed routinely during some heart operations. However, an alternative, more sustainable and large-scale source of thymus tissue must be found before this type of treatment can become routine.
We plan to:
For further information about the different types of stem cells used in our work, take a look at the fact sheets available from EuroStemCell.